病毒唑超声雾化吸入治疗80例小儿呼吸道感染疗效分析

Curative effect analysis on ribavirin ultrasound aerosolized treatment to 80 pediatric respiratory infections patients

目的分析并评价病毒唑超声雾化吸入治疗小儿呼吸道合胞病毒感染的临床疗效。方法对我院自2008年10月-2010年12月期间收治的80例呼吸道合胞病毒感染患儿进行随机分组，在相同的治疗条件下，观察组40例进行病毒唑超声雾化吸入治疗，对照组40例进行病毒唑静脉滴注治疗。结果观察组总有效率为80．0％，明显高于对照组的42．5％，差异有极显著性（P〈0．01）。对照组的发热持续时间、喘息时间、肺部湿罗音以及哮鸣音持续时间均长于观察组，差异有极显著性（p〈0．01）。结论病毒唑雾化吸入方式在治疗呼吸道合胞病毒感染方面的临床疗效明显好于病毒唑静脉滴注治疗。

Objective To analyze and evaluate the curative effect of ribavirin ultrasound aerosolized in treating pediatric respiratory syncytial virus （RSV） infection. Methods 80 cases of RSV infection from Oct 2008 to Dec 2010 were randomly divided into control group and experiment group, with 40 cases for each group. The experiment group used ribavirin ultrasound treatment, while the control group took ribavirin intravenous drip treatment. Results The effective rate in experiment group total was 80.0%, significantly higher than that of the control group （42.5%） （ X2= 26.02, P〈 0.01 ）, with statistical significance.The fever duration, break time, and lung sound duration in control group were significantly longer than those of experiment group （P 〈 0.01）. Conclusion The clinical curative effects of the method of ribavirin ultrasound aerosolized in the treatment for RSV infection are obviously better than ribavirin intravenous drip treatment.