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轻度认知功能损害的研究进展

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摘要 随着社会人口的老龄化,老年痴呆的患病率不断升高,其中阿尔茨海默病(Alzheimer's disease,AD)是老年痴呆中最常见的.轻度认知功能障碍(mild cognitiveimpairment,MCI)是正常衰老和痴呆的中间状态[1],是痴呆特别是AD的高危人群.它向AD的年转化率是正常人群的10 倍[2].有报道,MCI 患者最终都会转为AD 或其他形式的痴呆[3].许多研究也认为MCI阶段是防治老年痴呆的关键阶段[4-5].MCI 概念的提出,为AD的早期治疗和干预提供了新的靶点,是AD研究的重要进步.
作者 于恩彦
出处 《浙江医学》 CAS 2012年第3期153-158,168,共7页 Zhejiang Medical Journal
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