不同地理环境下7—14万健康青少年24小时尿肌酐排泄量的测定及分析

A Study on the amount of creatinine excreted by urine from healthy adolescents Lived in different topographies Henan province

本文对河南省地甲病流行地区不同劳动强度7—14岁健康青少年24小时尿肌酐排泄量进行了测定和分析。从1440份样品测定结果表明:7—14岁男、女各年龄组24小时尿肌酐排泄量为山区明显高于丘陵和平原(P>0.05);24小时尿肌酐排泄量随年龄、体重的增大而增多,相关分析均呈高度正相关,P<0.001,有非常显著性意义;在两性之间各年龄组肌酐均值均为男>女;7—12岁男、女24小时尿肌酐均值均低于成人,13—14岁男、女均值接近成人。因而我们建议:对7—14岁人群使用午后一次随机尿样在换算24小时总尿碘量时,肌酐系数应采用不同地形、不同性别、年龄的相应肌酐系数,13—14岁男、女青少年也可采用成人肌酐系数。

This paper gives an account of determination and analysis of the amountof creatinine excreted by urine in 24 hours from healthy adolescents at ages 7-14lived in endemic goiter area with different topographies Henan province.The re-sults from 1440 samples showed that the amounts of creatinine in urine in 24hours excreted from each age-group(7-14)boys or girls who lived inmountainous areas were higher than that of lived in hill and plain areas signifi-cantly(P<0.05)。It got higher with growth of age and weight,showing highlypositive correlation(p<0.001)。The mean amount of creatinine of each age-group of male was higher than that of female;of the adolescents at ages 7-12(boys and girls);the mean amount of creatinine was lower than that of adults;the mean amount of creatinine of the adolescents at ages 13-14(boys and girls)was approached to that of adults。So that we suggest:When calculating the totalamount of urinary iodine in 24 hours for adolescents at ages 7-14 by randomlysampling an afternoon urine,we should respectively take proper coefficient ofcreatinine according to different topographies and different sexes and ages,and itis also available to take the adult's creatinine coefficent for the adolescents atages 13-14.