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氟骨症病人尿液中羟脯氨酸含量测定 被引量:7

Preiiminary study of content of hydroxyproline in urine in endemic skeletal fluorosis
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摘要 本文测定了39例氟骨症病人尿液中羟脯氨酸及尿氟含量。发现氟骨症病人尿液中羟脯氨酸含量显著高于同年龄组的正常人,且与尿氟呈显著正相关关系。说明氟骨症病人体内胶原代谢加快,含量减少,尿羟脯氨酸排泄增多,并与尿氟含量有关。 This article reported that the content of hydroxyproline and fluoride inurine in 39 cases is tested.It is found that the content of hydroxyproline inurine of patient who suffer from endemic skeletal fluorosis is much higher thanthose of normal people in same age,relation between hydroxyproline and thecontent of fluoride in urine is significant positive correlation.It shows thatmetabolism of collagen increases,the content of collagen reduces in the patientwho suffer from endemic skeletal fluorosis,Also discharge of hydroxyprolinein urine increases,which has relation with the content of fluoride in urine.
作者 张聪恪
出处 《中国地方病学杂志》 CAS CSCD 1990年第6期340-342,共3页 Chinese Jouranl of Endemiology
关键词 氟骨症 羟脯氨酸 胶原 尿氟 Endemic skeletal fluorosis Hydroxyproline Collagen Fluoride in urine
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参考文献4

  • 1白学信,赖安兰,杨华智,张秀丽,周定友,梁代华.99例氟骨症在脱离高氟后的尿氟排泄动态观察[J]中国地方病学杂志,1988(04).
  • 2刘昌汉等.地方性氟中毒防治指南[M]人民卫生出版社,1988.
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  • 4山东医学院生物化学教研室 编.人体疾病生化紊乱[M]人民卫生出版社,1978.

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