缬沙坦治疗慢性心力衰竭的临床疗效观察

目的探讨缬沙坦治疗慢性心力衰竭的疗效和安全性。方法选择冠心病缺血性心肌病、扩张型心肌病、高血压性心脏病、风湿性心脏病慢性心衰患者26例,在使用常规利尿剂、血管扩张剂、强心剂等治疗基础上加用血管紧张素Ⅱ受体拮抗剂缬沙坦口服,采用自身对照观察比较用药前、治疗后8周心脏指标变化,评估临床有效性及安全性。结果治疗8周后显效9例,有效15例,总有效率88%。无效2例,占12%。结论在常规治疗基础上加用缬沙坦治疗慢性心力衰竭效果显著,可改善心功能及临床症状,提高患者的生活质量。

Objective to study efficacy and safety of valsartan in the treatment of chronic heart failure health. Methods Selected coronary heart disease and ischemic heart disease, dilated cardiomyopathy, hyperten- sive heart disease, rheumatic heart disease in 26 patients with chronic heart failure, in the use of conventional di- uretics, vasodilator, tonic treatment on the basis of additional use of angiotensin II receptor antagonist valsartan o- ral, using their own control observation on comparative medicine cardiac changes before and 8 weeks of treatment to assess the clinical efficacy and safety. Results 8 weeks after treatment with Excellent 9 cases, effective 15 ca- ses, total effective rate 88%. Invalid 3, 12%. Conclusion In conventional treatment on the basis of significant additional use of valsartan in treatment of chronic heart failure can improve heart function and clinical symptoms, improve quality of life of patients.