子宫内膜息肉样腺肌瘤临床病理分析

Clinical pathologic analysis of endometrial polypoid adenomyoma

目的:探讨子宫内膜息肉样腺肌瘤的临床病理特征。方法:对27例子宫内膜息肉样腺肌瘤的临床资料和病理特征进行回顾性分析。结果:27例子宫内膜息肉样腺肌瘤于宫腔镜下未能确诊,经病理检查明确诊断。其中息肉样腺肌瘤15例,由富含平滑肌组织的基质包绕大小和形态不等的子宫内膜腺体,但无不典型性改变;非典型性息肉样腺肌瘤12例,由杂乱无章的不规则腺体构成,具有明显的腺体结构复杂性和细胞非典型性,可见鳞状上皮化生。结论:子宫内膜息肉样腺肌瘤具有特异的病理特征,为良性病变,但是非典型性息肉样腺肌瘤存在低度恶性潜能,需完整切除肿物,防止复发,且应严密随诊。

Objective： To analyze the clinical pathology of endometrial polypoid adenomyoma. Methods： The clinical data and pathological characteristics in 27 cases of endometrial polypoid adenomyoma were retrospectively analyzed. Results： Not all cases of endometrial polypoid adenomyoma, as diagnosed by pathological examination, could be diagnosed by hysteroscopy. This study encompassed 1S cases ofpolypoid adenomyoma and 12 cases of atypical polypoid adenomyoma. The endometrial glands of polypoid adenomyoma, whose surrounding were rich in smooth muscle tissue of the matrix, were of different size and morphology, but otherwise showed no typical changes. The endometrial glands of atypical polypoid adenomyoma, in contrast, were irregular. There was conspicuous structural complexity to the glands and atypical cells. Occasionally, squamous metaplasia was obseved. Conclusion： Endometrial polypoid adenomyoma, a benign tumor in the clinical course, has specific pathological features, but atypical polypoidadenomyoma has low malignant potential. It should be completely removed and closely followed up.