亚临床甲状腺功能减退与糖尿病血管并发症

Subclinical hypothyroidism and diabetic vascular complications

亚临床甲状腺功能减退(亚临床甲减)是一种隐蔽而持久的内分泌代谢性疾病,其与糖尿病常合并存在。近年来,亚临床甲减作为糖尿病血管并发症的危险因素受到广泛重视。大多数研究认为亚临床甲减可通过影响血脂代谢、破坏凝血纤溶系统以及升高同型半胱氨酸和高敏C反应蛋白等糖尿病血管并发症的危险因素,参与和加重糖尿病血管并发症的发生、发展过程。

Subdinical hypothyroidism is a hidden and long-lasting endocrine and metabolic disease, which often coexists with diabetes mellitus. In recent years, subclinical hypothyroidism as a risk factor for diabetic vascular complications has received widespread attention. Most studies suggest that subclinical hypothyroidism affects the disturbance of lipid profile, damages the coagulation system and increases homocysteine and high sensitivity C-reactive protein. Such changes are involved in the development and progression of diabetic vascular complications.