摘要
A short and efficient synthesis of（Z）-2-substituted-5-（4-（（2-substitued-5-oxoimidazolidin-4-ylidene）methyl）benzamido）ben-zoic acid derivatives（8a-g） as potential type of FabH inhibitors is described.Their structures were confirmed by MS,NOE and ~1H NMR.
A short and efficient synthesis of（Z）-2-substituted-5-（4-（（2-substitued-5-oxoimidazolidin-4-ylidene）methyl）benzamido）ben-zoic acid derivatives（8a-g） as potential type of FabH inhibitors is described.Their structures were confirmed by MS,NOE and ~1H NMR.
基金
supported by the National High Technology Research and Development Program of China(No2006AA020601)
