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Glycerol mediated synthesis of 5-substituted lH-tetrazole under catalyst free conditions 被引量:2

Glycerol mediated synthesis of 5-substituted lH-tetrazole under catalyst free conditions
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摘要 We have developed simple,cost effective and environmentally benign protocol for the synthesis of 5-substituted 1H-tetrazoles via[2,3]cycloaddition reaction from organic nitriles and sodium azide in glycerol under catalyst free condition.The corresponding 5-substituted 1H-tetrazoles were obtained with good to excellent yields(68-95%). We have developed simple,cost effective and environmentally benign protocol for the synthesis of 5-substituted 1H-tetrazoles via[2,3]cycloaddition reaction from organic nitriles and sodium azide in glycerol under catalyst free condition.The corresponding 5-substituted 1H-tetrazoles were obtained with good to excellent yields(68-95%).
出处 《Chinese Chemical Letters》 SCIE CAS CSCD 2012年第2期161-164,共4页 中国化学快报(英文版)
基金 support from Department of Atomic Energy-Board of Research in Nuclear Sciences(DAE-BRNS)(No2009/37/39/BRNS/2268)
关键词 5-Substituted 1H-tetrazole [3+2]Cycloaddition Nitriles Glycerol Catalyst free 5-Substituted 1H-tetrazole [3+2]Cycloaddition Nitriles Glycerol Catalyst free
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