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磺脲类药物的低血糖风险 被引量:9

The risk of hypoglycaemia in sulfonylureas drugs
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摘要 磺脲类药物(SUs)是目前临床上应用最广泛的一类降糖药物,其主要机制是通过关闭胰岛B细胞膜上钾离子依赖性的ATP通道来增加内源性的胰岛素分泌,从而降低血糖。此外,随着葡萄糖钳夹技术的广泛应用,有研究发现磺脲类药物可使人体外周葡萄糖利用率提高10%~52%,提示磺脲类药物可能还具有不同程度的内在拟胰岛素作用。
出处 《药品评价》 CAS 2012年第4期28-32,共5页 Drug Evaluation
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参考文献20

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二级参考文献32

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共引文献119

同被引文献128

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