非风湿性心脏病引起的房颤患者并发脑栓塞相关因素分析

探讨非风湿性心脏病引起的房颤并发脑栓塞的相关因素。方法221例非风湿性心脏病房颤患者，按是否新发生脑栓塞分为脑栓塞组（92例）和无脑栓塞组（129例）两组，分析非风湿性心脏病引起的房颤并发脑栓塞与患者的年龄、性别及高血压、糖尿病、吸烟、饮酒、卒中史、冠心病、心力衰竭、前白蛋白（PAB）、尿酸等的关系。结果与非脑栓塞组相比，脑栓塞组患者年龄较大，女性、卒中史、PAB降低及合并高血压病、糖尿病者比例高，两组差异有统计学意义（P〈0．01），在吸烟、饮酒、冠心病、血脂异常、心力衰竭、尿酸方面差异无统计学意义（P〉0．05）。多因素Logistic分析显示，年龄1〉75岁、有高血压病和卒中史是脑栓塞的独立危险因素。结论非风湿性心脏病房颤引起的脑栓塞患者，独立相关因素为年龄、女性、高血压病史、卒中史；前白蛋白（PAB）降低和并发糖尿病为相关因素。

Objective Analysis on related factors of non - rheumatic atrial fibrillation in patients with cerebral embolism. Methods The 221 cases of non - rheumatic atrial fibrillation in patients with cerebral embolism were divided into two groups according to whether the embolism was new： group of 92 cases of cerebral embolism, cerebral embolism group of 129 cases of non - retrospective analysis of the two groups in age, sex, hypertension, diabetes, smoking, alcohol consumption, stroke, coronary heart disease, heart failure, prealbumin （PAB） , uric acid in the difference. Results Compared with non -cerebral embolism, cerebral embolism in patients older women, stroke history, PAB reduce hypertension and diabetes were a high proportion of patients between the two groups was significant difference （P 〈 0. 01 ）. The two groups in smoking, alcohol consumption, coronary heart disease, dyslipidemia, heart failure, uric acid in the difference was not significant difference （ P 〉 0. 05 ）. Multivariate Logistic analysis： age 〉75 years of age, history of hypertension, history of stroke was an independent risk factor for cerebral embolism. Conclusions Non- rheumatic atrial fibrillation in patients with cerebral embolism caused by factors independently associates with age, female, history of hypertension, stroke history ; PAB lower, non - rheumatic atrial fibrillation leading to diabetes mellitus are complicated by cerebral embolism related factors.