非淋菌性尿道炎患者HSV-2型抗体的检测分析

Detection and Analysis on HSV-2 Antibody in Patients with Nongonococcal Urethritis

目的:检测非淋菌性尿道炎(NGU)患者HSV-2型抗体阳性率,探讨其是否高于正常人群。方法:应用酶联免疫法(ELISA)分别检测104例NGU患者血清中HSV-2抗体以及68例正常体检人群血清中的HSV-2抗体。结果:104例NGU患者中,检出HSV-2IgM或(及)IgG感染35例,检出率33.65%;68例健康体检者中,检出HSV-2IgM或(及)IgG阳性5例,检出率5.62%,两者有显著性差异。NGU患者中,女性阳性率为30.56%,男性阳性率为35.29%.两者无显著性差异。NGU患者中,HSV-2IgM与IgG检出率有显著性差异。结论:在非淋菌性尿道炎患者中,HSV-2感染阳性率高于正常人群,须引起临床注意。

Objective To detect the HSV-2 antibody in nongonococcal urethritis（NGU） patients to investigate if the positive detection rate is higher than that in health adults. Methods HSV-2 antibody in the serum of 104 patients with NGU and 68 health adults were detected by ELISA. Results Among 104 NGU patients, HSV-2 IgM or （and） HSV-2 IgG infection was founded in 35 patients. The positive detection rate was 33.65%. Among 68 cases of health examination, HSV-2 IgM or （and） HSV-2 IgG infection was founded in 5 cases. The positive detection rate was 5.62%. There was significant difference between the positive detection rate of NGU patients and that of the people of health examination. Among NGU patients, the positive detection rate was 30.56% in female patients and 35.29% in male patients, there were no significant difference between the positive detection rate of male and female. Among NGU patients, there were significant differences between the positive detection rate of HSV-2 IgM and the positive detection rate HSV-2 IgG. Conclusion The infection rate of HSV-2 of patients with NGU was higher than that of normal health people. Physician should pay more attention on this fact.