贵州省2006-2010年脑膜炎球菌疫苗接种情况分析

Analysis on Meningococcal vaccine's inoculation in Guizhou Province(2008-2010)

目的分析贵州省2006-2010年脑膜炎球菌疫苗(MenV)接种情况,为预防控制流行性脑脊髓膜炎制定策略和措施提供依据。方法分析评估报告数据,对病例开展回顾性调查。结果贵州省2006-2010年共报告接种A群MenV第1针227.2万剂次,第2针144.8万剂次,第1针与第2针的估算接种率分为41.3%～130.1%和23.1%～107.4%。全省报告接种A+C群MenV第1针119.6万剂次,第2针42.7万剂次,第1针与第2针的估算接种率分为47.5%～101.2%和11.2%～34.9%。2008-2010年流脑病例107例,有A群MenV免疫史的12例,有A+C群MenV免疫史的仅1例。结论贵州省MenV接种率不断提高,但是A+C群MenV接种情况不理想,应加强A+C群MenV的接种,提高接种率。

Objective To analyze e the Meningococcal vaccine＇s inoculation in Guizhou province during the period of 2006-2010,so as to e improve the strategies and measures to control e epidemic cerebrospinal meningitis.Methods The reported data were nalyzed,and a retrospective investigation was carried out.Results During the year from 2006 to 2010,the reported number of the first injection was 2 272 thousands（group A Meningococcal vaccine）,The reported number of the second injection was 1 448 thousands.The estimated coverage rate of the first injection of the group A Meningococcal vaccine was 41.3%-130.1%,and the s estimated coverage rate of the second injection was 23.1%-107.4 %.From 2008 to 2010,the reported number of the first injection was 1 196 000（group A and C Meningococcal vaccine） The reported number of the second injection was 427 000.The estimated rate of the first injection（group A and C Meningococcal vaccine） was 47.5%-101.2%,and the estimated coverage rate of the second injection was 11.2%-34.9%.There were 107 cases of eEpidemic cerebrospinal meningitis reported in Guizhou province during the year from 2008-2010,in which 12 cases had the group A Meningococcal vaccine＇s vaccination history,and only one case had the group A and C Meningococcal vaccine＇s vaccination history.Conclusions The vaccination coverage rate of Meningococcal vaccine increased gradually from 2006-2010,and the morbidity rate of epeidemic cerebrospinal meningitis decreased significantly.However,the vaccination coverage rate of group A and C Meningococcal vaccine was unsatisfactory.The epidemic risk of Epidemic cerebrospinal meningitis still existed.The group A and C Meningococcal vaccine＇s inoculation coverage rates should be promoted in Guizhou province.