宁夏职业人群MS流行特征及影响因素分析

Prevalence and risk factors of metabolic syndrome among occupational populations of Ningxia

目的了解宁夏职业人群代谢综合征(MS)的流行现状及相关危险因素。方法应用分层整群抽样方法,选择2009年3-10月至宁夏医科大学附属医院进行健康检查的3 191人,按2004年中华医学会糖尿病学分会(CDS)的MS诊断标准进行判定并分析。结果 MS总体患病率为17.2%(550/3 191),标化患病率为10.7%,随着年龄的增长患病率呈增加趋势(χ2=137.110、52.8661、22.850,P<0.01);男性MS患病率为25.2%(481/1 905),明显高于女性5.4%(69/1 286)(χ2=212.781,P<0.01),汉族人群为17.5%(471/2 685),高于回族人群14.9%(64/428)(u=1.172 2,P<0.05),已婚人群为18.6%(521/2 794),高于未婚人群5.2%(16/308)(χ2=35.071,P<0.01),干部人群为15.2%(353/1 896),高于工人人群15.2%(197/1 295)(χ2=6.257,P<0.05);MS患病率随着体质指数和腰围增长而增加;男性、≥50岁、饮酒、肥胖(高BMI或高腰围)、高血压、高甘油三酯、高血糖、高血尿酸、白细胞水平较高、高天冬氨酸氨基转移酶、高丙氨酸氨基转氨酶为MS的危险因素,高学历和高密度脂蛋白-胆固醇(High-density lipopro-tein cholesterol,HDL-C)为MS的保护因素。结论宁夏职业人群MS患病率较高,并且是多重危险因素共同作用的结果。

Objective To investigate the prevalence and associated risk factors of metabolic syndrome（MS） among occupational populations of Ningxia.Methods The workers taking routine health check-up were recruited for a questionnaire survey,physical examination,and laboratory test.MS cases were identified according to the definition of China Diabetes Society（CDS）.Results The crude prevalence rate of MS was 17.2%,with an age-adjusted prevalence rates of 10.7%.The rate of MS increased with the increment of age（P0.01） and the prevalence rate of the male（25.2%） was obviously higher than that of the female（15.6%）（P0.01）.The prevalence rate of MS in the Han nationality（17.5%） was higher than that in the Hui（14.9%）（P0.05） and the prevalence rate in the married（18.6%） was higher than that in unmarried（5.2%）（P0.01）.The prevalence rate in the cadres（18.6%） was higher than that in workers（15.2%）（P0.05）.The rate of MS increased with increments of body mass index（BMI） and waist circumference（WC）（P0.01）.The analyses of multivariate logistic regression showed that the risk factors of MS were male,fifty years old,alcohol drinking,obesity,high systolic blood pressure,high diastolic blood pressure,high triglyceride,high fasting plasma glucose,high uric acid,high white blood cell,and high levels of aspartate aminotransferase and alunine aminotransferase and the protective factors were education and high content of high-density lipoprotein.Conclusion There is a high prevalence rate of MS among Ningxia occupational populations and metabolic syndrome is the common result of a variety of risk factors.