2型糖尿病所致不同程度肾功能不全与骨质疏松发生的相关性研究

The clinical research of correlation between different kidney function damage causal by type 2 diabetes and the occurrence of osteoporosis

目的探讨2型糖尿病所致不同程度肾功能异常与骨质疏松发生的相关性。方法收集112例2型糖尿病肾功不全患者资料，并进行肾功能损害程度相关生化指标及不同部位骨密度、骨质疏松情况测定．采用统计学方法对比分析不同程度肾功能损害与骨质疏松发生的相关性。结果112例2型糖尿病不同程度肾功能损害患者中，随着肾功能损害程度的加重．骨质疏松发生严重程度也逐渐加重，骨质疏松发生率分别为33．3％，44．8％，56．5％，80．0％，差异有统计学意义（P〈0．05）。结论2型糖尿病所致不同程度肾功能损害与骨质疏松发生具有相关性。为了更好地控制骨质疏松的发生率，应努力控制并减轻2型糖尿病患者的肾功能损害程度。

Objective To analyze the Correlation between different kidney function damage caused by type 2 diabetes and the occurrence of osteoporosis. Methods Collect tbe clinical data of 112 patients of type 2 diabetes during the Sep. 2008 to Mar.2011 ,and proceed statistical exainination of kidney function and bone mineral density from different location. Analyze the correlation between different kidney function damage caused by type 2 diabetes and the occurrence of osteoporosis by using statistical software. Results Among all different kidney function damage caused by type 2 diabetes, the order of severity of occurrence of osteoporosis was increasing in pace with the more severe damaging kidney function. There was a significant difference between the two samples（ 33.3% ,44.8% ,56. 5% ,80.0%, P 〈 0.05）. Conclusion The correlation between different kidney function damage caused by type 2 diabetes was positively correlated with the occurrence of osteoporosis. We should strengthen to control and cure the patient＇s kidney function damage to decrease the occurrence of osteoporosis.