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A Green Route for the One-Pot Synthesis of 1,2-Disubstituted Benzimidazoles Using Iron(Ill) Phosphate under Solventless Conditions

A Green Route for the One-Pot Synthesis of 1,2-Disubstituted Benzimidazoles Using Iron(Ill) Phosphate under Solventless Conditions
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摘要 1,2-Disubstituted benzimidazoles are selectively synthesized in high yields under extremely mild conditions via the condensation of o-phenylenediamine derivatives with aldehyde derivatives using catalytic amount of iron(Ⅲ) phosphate under solventfree conditions. The use of readily available iron(Ⅲ) phosphate as a reusable and recyelable catalyst makes this process quite simple, convenient, and environment-friendly. 1,2-Disubstituted benzimidazoles are selectively synthesized in high yields under extremely mild conditions via the condensation of o-phenylenediamine derivatives with aldehyde derivatives using catalytic amount of iron(Ⅲ) phosphate under solventfree conditions. The use of readily available iron(Ⅲ) phosphate as a reusable and recyelable catalyst makes this process quite simple, convenient, and environment-friendly.
出处 《Chinese Journal of Chemistry》 SCIE CAS CSCD 2012年第1期65-70,共6页 中国化学(英文版)
关键词 1 2-disubstituted benzimidazoles iron(Ill) phosphate solvent-free 1,2-disubstituted benzimidazoles, iron(Ill) phosphate, solvent-free
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