摘要
1,2-Disubstituted benzimidazoles are selectively synthesized in high yields under extremely mild conditions via the condensation of o-phenylenediamine derivatives with aldehyde derivatives using catalytic amount of iron(Ⅲ) phosphate under solventfree conditions. The use of readily available iron(Ⅲ) phosphate as a reusable and recyelable catalyst makes this process quite simple, convenient, and environment-friendly.
1,2-Disubstituted benzimidazoles are selectively synthesized in high yields under extremely mild conditions via the condensation of o-phenylenediamine derivatives with aldehyde derivatives using catalytic amount of iron(Ⅲ) phosphate under solventfree conditions. The use of readily available iron(Ⅲ) phosphate as a reusable and recyelable catalyst makes this process quite simple, convenient, and environment-friendly.