皂苷Tb 2个糖基化产物的NMR研究

An NMR Study on Two Glucosylated Steroidal Saponins of Tb

利用1 H NMR、13 C NMR、COSY、HSQC和HMBC等多种核磁共振技术,结合MS技术,确认了皂苷Tb的2个糖基化产物的结构,即偏诺皂苷元-3-O-α-D-葡萄糖-(1→3)-[α-L-鼠李糖-(1→2)]-β-D-葡萄糖苷(1)和偏诺皂苷元-3-O-α-D-葡萄糖-(1→4)-α-D-葡萄糖-(1→3)-[α-L-鼠李糖-(1→2)]-β-D-葡萄糖苷(2).化合物1和2为新化合物,对其1 H NMR和13 CNMR信号分别进行了全归属和详细分析.

Two glucosylated steroidal saponins of Tb were elucidated as pennogenin-3-O-α-D-glucopyranosyl-（1→3）-[α-L-rhamnopyranosyl-（1→2）]-β-D-glucopyranoside（1）,and pennogenin-3-O-α-D-glucopyranosyl-（1→4）-α-D-glucopyranosyl-（1→3）-[α-L-rhamnopyranosyl-（1→2）]-β-D-glucopyrannoside（2） by MS,1H NMR,13C NMR,COSY,HSQC and HMBC analysis.1 and 2 are new compounds.The 13C-and 1H NMR chemical shifts of these two new compounds were assigned.