东莞市首起社区登革热暴发疫情流行病学调查

Epidemiological investigation on the first outbreak of dengue fever in a community of Dongguan City

目的:对东莞市首起登革热社区暴发疫情进行调查分析。方法:采用现场流行病学调查方法了解疫情波及范围、病例分布情况及可能传播来源;采用ELISA法进行登革热IgM抗体检测。结果:2010年7月22日～10月26日,东莞市兴塘社区发生了一起登革热社区暴发疫情,共报告病例40例,其中确诊病例24例,可疑病例16例;病例的主要临床特征为发热(92.50%)、头痛(82.50%),血小板及白细胞减少分别占57.50%和52.50%;病例表现为首发病例住家200米范围内的聚集性;首发病例发病前有东南亚国家旅游史。结论:症状不典型输入性病例容易引起本土疫情,人员的高流动性易造成登革热疫情的扩散;控制疫情的关键是开展灭蚊和清除蚊虫孳生地的工作并在短时间内将布雷图指数降至5以下的水平。

Objective： To investigate and analyze the epidemiologic features of the first outbreak of dengue fever in certain community of Dongguan city,Guangdong province.Methods： We conducted the field epidemiological investigation on the affected areas,distribution and sources attributable to the infection of the outbreak.Enzyme linked immunosorbent assay（ELISA） was used to detect IgM antibody in patients with dengue fever.Results： During Jul.22 and Oct.26 of 2010,a dengue fever outbreak occurred in Xingtang community of Dongguan city.Report of the infectious disease was 40 cases,in which 24 were final diagnosis as dengue fever and 16,suspected cases.The common clinical symptoms of this disease were characterized by fever（92.50%）,headache（82.50%）,leukopenia（57.50%） and thrombocytopenia（52.50%）.Cases aggregated around the house of the first case within a space of some 200 meters,and the first case had ever traveled in some Southeast Asia countries.Conclusion：Asymptomatic imported case is predisposed to a local outbreak of dengue,and frequent population migration tends to cause spreading of this disease.The effective way to prevent dengue virus transmission is to combat the disease-carrying mosquitoes and keep Breteau Index under the level of 5.