100例哮喘患儿发病的危险因素调查及Logistic回归分析

Survey on risk factors for 100 cases of asthma infants and Logistic regression analysis

目的对哮喘患儿发病的危险因素进行分析，为儿童哮喘的防治提供进一步的参考依据，降低其发病率。方法选取我院2009年1月～2011年1月收治的100例哮喘患儿作为调查研究对象。同时选择同期来我院门诊体检的年龄、性别相匹配的100例非哮喘性疾病患儿设立为对照组，对100例哮喘患儿发病的危险因素进行调查研究。结果哮喘儿童有患儿或家族过敏史及家族哮喘史、由气候变化、物理刺激、异味等环境因素以及呼吸道感染等诱因、接受纯母乳喂养比率少等均与儿童哮喘的发病密切相关（P〈0．05），而与居室装修情况无关（P〉0．05），采用Logistic回归分析对单因素分析中有意义的危险因素进行分析，结果表明，哮喘儿科及家族过敏史以及家族哮喘史、环境因素如气候变化、物理刺激、异味等以及≥6次／年的呼吸道感染史、母乳喂养比率少等均为哮喘儿童发病的重要的危险因素。结论导致儿童哮喘发病以及加重的危险因素多种多样，是今后对儿童哮喘研究的重要课题之一，从而为儿童哮喘的防治提供进一步的参考依据，降低其发病率。

Objective The incidence of asthma risk factors were analyzed for the prevention and treatment of asthma in children provide further reference, to reduce its incidence. Methods All 100 cases of children with asthma treated as a research object in our hospital in January 2009-January 2011. At the same time, 100 cases of non-asthmatic children with physical examination of the age and sex-matched were chose as control group, 100 cases of asthma disease risk factors research. Results Children with asthma or family history of allergies in children, and family history of asthma, from climate change, physical stimulation, odor and other environmental factors and respiratory infections and other incentives to accept low rates of exclusive breastfeeding etc, is closely related to the incidence of asthma in children （P 〈 0.05）, and nothing to do with the fitting room （P 〉 0.05）, using Logistic regression analysis of univariate analysis, significant risk factors were analyzed, the results show that pediatric asthma and family history of allergies and family history of asthma, environmental factors such as climate change, physical stimulation, smell, and ≥6 times / year history of respiratory tract infections, breast-feeding rate and less incidence of asthma in children are important risk factors. Conclusion The incidence of child- hood asthma and lead to increased risk of a variety of factors, asthma in children is our future study of the important issues, so as to provide further prevention and treatment of asthma in children of reference, to reduce its incidence.