普米克令舒联合特布他林雾化治疗小儿毛细支气管炎

Pulmicort respules combined with terbutaline to treat bronchiolitis pediatric bronchiolitis in nebulization therapy

目的探讨普米克令舒联合特布他林雾化吸入治疗婴幼儿毛细支气管炎的临床疗效。方法选取98例确诊为毛细支气管炎的患儿,随机分为试验组和对照组各49例,所有患儿均采取综合治疗;在此基础上,试验组予以用普米克令舒1 mL+0.25%特布他林1 mL雾化吸入,每日2次,生理盐水2 mL+盐酸氨溴索15 mg雾化吸入,每日1次,连续使用7 d为1个疗程。对照组仅予生理盐水2 mL+盐酸氨溴索15 mg雾化吸入,每日1次。结果经过治疗后,试验组临床症状、肺部体征消失的时间均明显短于对照组,住院时间也短于对照组(P<0.05)。且试验组的治愈率为93.88%,明显高于对照组(63.27%)(χ2=12.844,P<0.05)。结论除了对婴儿毛细支气管炎予以常规综合治疗,普米克令舒联合特布他林雾化吸入能够明显迅速改善临床症状,减少住院时间,值得临床推广。

Objective To observe and discuss the effect and value of the combination of pulmicort respules and terbutaline to treat the bronchiolitis in nebulization therapy. Methods Selected 98 cases of bronchiolitis pediatric patients and they were randomly divided into experimental group and matched group. Besides comprehensive treatment, experimental group： used pulmicort respules 1 mL＋0.25% terbutaline 1 mL as nebulization therapy,twice a day;ambroxol 2 mL once a day. Those were used 7 days as a course;matched group：only used ambroxol 2 mL as nebulization therapy,twice a day. Results After the treatment, the lasting time of clinical symptoms,lung signs in experimental group was significantly shorter than that in matched group,and the same as the length of stay （P 〈 0.05）. The cure rate of experimental group was 93.88% which was significantly higher than matched group （63.27%） （P 〈 0.05）. Conclusion Besides the normal comprehensive treatment,we can use the combination of pulmicort respules and terbutaline to treat bronchiolitis pediatric patients. It can obviously improve the clinical symptoms, shorten the course of disease. So it deserve generalization.