摘要
甲状腺激素在维持肾脏的发育、正常结构、水和电解质平衡、肾小球滤过率等方面发挥着重要作用。甲状腺功能异常时上述肾脏功能发生相应变化。正常情况下,肾脏可清除甲状腺激素,肾病综合征、肾功能不全等疾病可影响甲状腺激素的合成、分泌、代谢与清除。甲状腺自身免疫性疾病常并发肾脏疾病,可能与共同的免疫机制有关。了解甲状腺功能异常与肾脏疾病的相互影响对于两种疾病的诊治都具有较大意义。
Thyroid hormones are important regulators of renal development,renal structure,GFR,and salt and water metabolism.On the other hand,kidney is involved in the metabolism and elimination of thyroid hormones.The decline of kidney function and nephrotic syndrome are accompanied by changes in the synthesis,secretion,metabolism,and elimination of thyroid hormones.Disorders of thyroid function have been also linked to development of immune-mediated glomerular disease.Further studies of mechanisms involved in thyroid disorders and kidney diseae are necessary.It is important to keep this association in mind for our physicians.
出处
《中国全科医学》
CAS
CSCD
北大核心
2012年第5期483-484,共2页
Chinese General Practice
关键词
甲状腺激素
肾功能不全
慢性
肾病综合征
Thyroid hormones
Renal insufficincy
chronic
Nephrotic syndrome
