上胸椎前路钛板与颈前路钛板内固定装置的拔出强度实验

Plate pull-out strength of upper thoracic anterior titanium plate and anterior cervical titanium plate fixed system

背景：目前尚无专门用于上胸椎前路的内固定器械,课题组自行研制的内固定器械已申请了专利,仍在进一步研究当中。目的：对自行研制的上胸椎前路钛板内固定装置与颈椎前路Orion钛板内固定装置拔出强度进行比较,探讨上胸椎前路钛板固定的可行性。方法：6例新鲜成人T2~T4尸体标本随机分为两组,即上胸椎前路钛板内固定组,颈椎前路Orion钛板内固定组,切除T3椎体和T2/3、T3/4椎间盘组织,同一尸体髂骨上取适当大小的骨块植入T3椎体缺损处,然后分别安装好内固定,在生物力学试验机上通过传感器测出固定钛板的最大拔出力并进行统计学分析。结果与结论：上胸椎前路钛板内固定装置最大拔出力平均（1005.11±252.78）N,强于颈椎前路Orion钛板内固定装置（469.37±142.75）N,差异有显著性意义（P〈0.05）。可见自行研制的上胸椎前路钛板内固定装置拔出强度优于颈椎前路Orion钛板内固定装置,由此推断上胸椎前路内固定装置是比较牢固的,为后期临床应用奠定了实验基础。

BACKGROUND： There is no dedicated upper thoracic anterior fixed system, the fixation devices deceloped by ourself has applied for a patent, which is still in the further research. OBJECTIVE： To evaluate the pull-out strength of self-designed upper thoracic anterior titanium plate fixed system and Orion anterior cervical titanium plate fixed system and to explore whether the upper thoracic anterior titanium plate fixation is feasible. METHODS： Intact T2-T4 specimens from 6 fresh corpses were randomly divided into two groups： group A with upper thoracic anterior titanium plate fixation and group B with Orion anterior cervical plate fixation. T3 vertebral body and T2/3, T3/4 disc tissue were resected, then taken the appropriate iliac bone in the same body implanted in the T3 vertebral bone defect, and each of their fixation were installed.The pull-out strength was tested in the biomechanical testing machine and analyzed statistically. RESULTS AND CONCLUSION： The average pull-out strength of the group A was （1 005.11±252.78） N, and it was stronger than that of the group B （469.37±142.75） N, the difference was statistically significance （P 0.05）. The self-designed upper thoracic anterior titanium plate fixation device pull-out strength is superior to Orion anterior cervical titanium plate fixation device, which provided an experimental basis for later clinical application.