聚甲基丙烯酸与修饰聚丙烯酰胺间的络合作用

Complexation between Poly(methacrylic acid) and Cationically Modified Polyacrylamide

利用荧光各向异性、荧光探针和荧光猝灭等静态光物理技术研究了稀水溶液中聚甲基丙烯酸(PMAA)与阳离子修饰聚丙烯酰胺 (QCPAM )间的络合作用.结果表明 :在 pH=2 -8范围内 ,PMAA与QCPAM之间发生明显络合 ,但以 pH为4时络合作用最大 ,最佳络合配比为1:1(单体单元比 ) ,络合作用的发生大大地改变了PMAA的构象行为.PMAA构象对 pH和络合作用的双重依赖性有可能在新型“智能”凝胶的设计合成上获得应用.

The complexation between poly(methacrylic acid)(PMAA) and cationically modified polyacrylamide(QCPAM) was investigated by fluorescence anisotropy measurements, fluorescence probe studies and fluorescence quenching techniques. It has been demonstrated that the complexation occurs between pH 2 and 8, and the best conditions for complexation are pH 4 and complex ratio 1:1(PMAA:QCPAM, in monomer unit). In addition, along with the complexation,the conformation of PMAA changed dramatically. The pH and complexation dependences of the conformation of PMAA may find some uses in design and synthesis of “intelligent”polyelectrolyte gels.