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肠道病毒71型实验室诊断研究进展 被引量：2

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摘要 人肠道病毒71型（human enterovirus71，EV71）属于小RNA病毒科，基因组为单股正链RNA，最早是于1969—1970年问在美国加利福尼亚州发生中枢神经系统症状的婴儿粪便中分离得到，之后世界上许多国家相继报道了Ev71感染的流行，HFMD与Ev71感染的关系也受到了广泛的重视。
作者 王东旭 温红玲 王志玉
机构地区 济南山东大学公共卫生学院病毒学研究室
出处 《国际病毒学杂志》 2012年第1期44-47,共4页 International Journal of Virology
基金 国家自然科学基金（30901265） 山东省自然科学基金（ZR2010CQ030） 教育部博士点基金新教师基金（20090131120068） 山东大学公共卫生学院青年人才创新基金（GGWS200801）
关键词 关键词:人肠道病毒71型 手足口病 实验室诊断
分类号 R72 [医药卫生—儿科]
  • 相关文献

参考文献24

  • 1Schmidt NJ,Lennette EH,Ho HH.An apparently new enterovirus isolated from patients with disease of the central nervous system.J Infect Dis,1974,129(3):304-309.
  • 2McMinn PC.An overview of the evolution of enterovirus 71 and its clinical public health significance.FEMS Microbiol Rev,2002,26(1):91-107.
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  • 4严志平,何雅青,刘可,何建凡,张顺祥.深圳市南山区肠道病毒71型引起手足口病局部流行的初步调查[J].中国公共卫生,2001,17(7):645-645. 被引量：35
  • 5郭会杰,王潇潇(综述),李秀玲(审校).人类肠道病毒71型的研究进展[J].国际病毒学杂志,2010,17(4):97-101. 被引量：8
  • 6邵惠训.手足口病的现状与展望[J].国际病毒学杂志,2010,17(3):74-78. 被引量：69
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二级参考文献43

  • 1田波,段海生,荣一兵,周世力.肠道病毒71型分子流行病学研究进展[J].中国病毒学,2004,19(4):426-429. 被引量：90
  • 2Yao-Chi Chung,Jen-Huang Huang,Chia-Wei Lai,Heng-Chun Sheng,Shin-Ru Shih,Mei-Shang Ho,Yu-Chen Hu.Expression,purification and characterization of enterovirus-71 virus-like particles[J].World Journal of Gastroenterology,2006,12(6):921-927. 被引量：43
  • 3周世力,李琳琳,何雅青.深圳市肠道病毒71型血清流行病学初步调查[J].热带医学杂志,2007,7(1):66-67. 被引量：185
  • 4Lee TC,Guo HR et al.Diseases caused by Enterovirus 71 infection[J].Podia Infect Dis J,2009,28(10):904-910.
  • 5Canfosa MJ,Perera D et al.Molecular epidemiology of human Enterovirus 71 strains and recent outbreaks in the Asia Pacific Region:Comparative analysis of the VP1 and VP4 genes[J].Emerg Infect Dis,2003,9:461-468.
  • 6Fujimoto TM,Chikahira S et al.Outbreak of central nervous systern disease associated with hand.foot and mouth disease in Japan during the Summer of 2000:detection and molecular epidemiology of enterovirus 71[J].Microbiol Immunol,2002,46:621-627.
  • 7Holger F Rabenau,Matthias Richter et al.Hand,foot and mouth disease:semprevalence of Coxsackie A16 and enterovirus 71 in Germany[J].Med Micro and Immunol,2010,199(1):45-51.
  • 8Mitsuaki Hesoya,Yukihiko Kawasaki et al.Genetic diversity of Coxackie virus A16 associated with hand,foot,and mouth disease epidemics in Japan from 1983 to 2003(J).J Clin Micro,2007,45(1):112-120.
  • 9Munemura TM,Salkusa C et al.Genetic diversity of enterovirus 71 isolated from cases of hand,foot and mouth disease in Yokohama City between 1982 and 2000[J].Arch Virol,2003,148:253-263.
  • 10Tu PV,Thao NT et al.Epidemiologic and virologic investigation of hand,foot and mouth disease,Southern Vietnam[J].Emerg Infect Dis,2007,13(11):1733-1741.

共引文献194

同被引文献32

  • 1MeMinn PC. An overview of the evolution of entelovirus 71 and its clinical and public health significance [ J ]. FEMS Micnbiology Reviews, 2002, 26 ( 1 ) : 91-107.
  • 2Sylvain de Btxeyne, Bonderoff JM, Chumakov KM, et al. Cleavage of eukaryotic initiation factor elF5B by enterovirus 3C proteases [J]. Virology, 2008, 378( 1 ) : 118-122.
  • 3Weng KF, Li ML, Huang CT, et al. Enterovirus 71 3C protease cleaves a novel target CstF-64 and inhibits cellular polyadenylation [J]. PLoS Pathog, 2009, 5(9): e1000593.
  • 4Li M, Hsu T, Chen T, el al. The 3C prutease activity of enterovir- us 71 induces human neural cell apoptosis[ J ]. Virology, 2002, 293 (2) : 386-395.
  • 5Lei XB, Xiao X, Xue QIt, et al. Cleavage of interferon regulatory factor 7 by enterovirus 71 3C suppresses cellular responses [ J ]. J Virol, 2013, 87 (3) : 1690-1698.
  • 6Lei XB, Liu XL, Ma YJ, et al. The 3C protein of enterovirus 71 inhibits retinoid acid-inducible gene I-mediated interfernn regulato- ry factor 3 activation[J]. J Virol, 2010, 84 (16): 8051-8061.
  • 7Lei XB, Sun ZM, Liu XL, et al. Cleavage of the adaptor protein TRIF by entemvirus 71 3C inhibits antiviral responses mediated by Toll-like receptor 3 [ J ]. J Viral, 2011 , 85 ( 17 ) : 8811-8818.
  • 8Hacker H, Redecke V, Blagoev B, et al. Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6[J]. Nature, 2006, 439 (7073): 204-207.
  • 9Shih SR, Chiang C, Chen TC, et al. Mutations at KFRDI and VGK domains of enterovirus 71 3C protease affect its RNA bind- ing and proteolytic activities[J]. J Biomed Sci, 2004, 11 (2) : 239 -248.
  • 10Oganesyan G, Saha SK, Guo B, et al. Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral re- sponse[J]. Nature, 2006, 439 (7073): 208-211.

引证文献2

二级引证文献3

国际病毒学杂志
2012年 第1期

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