忽视症患者对不同情绪面孔注意偏移的研究

Effect of expressional chimeric faces on the attentional bias in neglect patients

目的探讨忽视症（Unilateral Spatial Neglect，USN）患者在不同情绪面孔条件下的注意偏移情况。方法将12例USN患者和与其人口学资料相匹配的30名健康志愿者（HC组）作为研究对象，采用高兴-中性和悲伤．中性情绪面孔嵌合图形（ExpressionalChimericFaces，ECF）进行注意偏移度测查。结果USN患者在高兴-中性和悲伤-中性ECF试验中注意偏移度分别为（0．78±0．22）分和（0．50±0．20）分，HC组在高兴．中性和悲伤-中性ECF试验中注意偏移度分别为（-0．31±0．20）分和（-0．25±0．17）分，USN组注意右偏，HC组注意左偏，两组间差异有统计学意义（高兴-中性ECF：江15．550，P〈0．01；悲伤-中性ECF：t=12．192，P〈0．01）；组内比较发现USN组在悲伤-中性ECF试验中注意右偏程度小于高兴-中性ECF（t=3．954，P=0．002）；而HC组在高兴-中性和悲伤-中性ECF试验中注意偏移度差异无统计学意义（t=-1．302，P=0．203）。结论USN患者注意右偏；但对悲伤-中性ECF注意右偏程度显著减小。这可能与USN患者对忽视侧情绪信息的意识下加工及半球对情绪认知的特点有关。

Objective To investigate the effect of expressional chimeric faces on the attentional bias in u- nilateral spatial neglect （USN） patients. Methods 12 USN patients and 30 matched healthy controls （HC） were involved in this study. All of them were performed with happy-neutral and sad-neutral expressional chimeric faces （ECF） and the attentional deviation scores were compared between and within groups. Results There were statistically significant differences of attentional deviation scores （ happy-neutral ECF ： t = 15. 550, P 〈 O. O1 ; sad- neutral ECF ： t = 12. 192, P 〈 0.01 ） between the USN group （ happy-neutral ECF ：0.78 ± 0.22 ; sad-neutral ECF ： O. 50 ± 0.20 ） and the HC group （ happy-neutral ECF ： - 0.31 ± 0.20 ; sad-neutral ECF ： - 0.25±0. 17 ）, with rightward bias in the USN group and small leftward bias in the HC group. For the USN group, the magnitude of rightward bias in the sad-neutral ECF condition was reduced than in the happy-neutral ECF condition （ t = 3. 954, P = 0. 002 ）. There were no statistically differences under happy-and sad-neutral ECF conditions within the HC group （ t = - 1. 302, P = 0. 203 ）. Conclusions USN patients show rightward attentional bias under both happy- and sad-neutral ECF conditions. However, the magnitude of rightward bias under the sad-neutral ECF condition are reduced significantly. This might be attributed to the unconscious processing of stimuli in the neglected side and emotion cognition of the brain hemispheres.