纳米金/石墨烯修饰电极的制备及其对多巴胺的测定

Fabrication of a gold nanoparticles-graphene modified electrode and its application for determination of dopamine

利用电化学还原方法制备纳米金/石墨烯修饰玻碳电极,研究了多巴胺(DA)在该修饰电极上的电化学行为,建立了电化学测定多巴胺的新方法。结果表明,在磷酸盐缓冲溶液中,此修饰电极对多巴胺的电化学响应具有很好的催化作用。利用差示脉冲伏安技术对多巴胺的电化学氧化进行定量分析,多巴胺的氧化峰电流与其浓度在1.0×10-7～1.0×10-5mol/L范围内呈良好的线性关系,检测限低至4.0×10-8mol/L。该修饰电极适于多巴胺的分析检测。

A gold nanoparticles-graphene modified glassy carbon electrode（AuNPs-graphene/GCE） was prepared through electrochemical reduction method and the electrochemical response of dopamine（DA） on this modified electrode was investigated.The research results showed that the modified electrode exhibited excellent electrocatalytic effect toward DA.Under the optimal experimental conditions,the oxidation peak current was proportional to the concentration of DA in the range from 1.0×10^-7 to 1.0×10^-5 mol/L with a correlation coefficient of 0.9948.The detection limit was 4.0×10^-8 mol/L.In brief,the AuNP-GP/GCE has the advantage of simple preparation,good reproducibility and high stability,thus,it is suitable for sensitive detection of dopamine.