异体血小板凝胶治疗重症压疮的康复机制初探

PRELIMINARY STUDY OF RECOVERY MECHANISM IN TREATMENT OF SEVERE PRESSURE ULCER BY ALLOGENEIC PLATELET GEL

目的：对异体血小板凝胶治疗重症压疮康复机制的初步探讨。方法：纳入符合标准的Ⅲ-Ⅳ期重症压疮13例患者共17处创面，对创面进行标准处理后，将异体血小板凝胶注射到溃疡面及窦道内，治疗前和治疗后（3d，7d，14d，28d或到创面愈合）进行压疮愈合量表评分、压疮面积和创面愈合率的测定。结果：压疮愈合量表评分分值明显减少，压疮面积明显减少，创面愈合率58．82％（10／17），显效率23．52％（4／17），有效率17．65％（3／17），无效率0。经统计学处理（秩和检验、t检验、X2检验）P〈0．05有统计学意义。结论：异体血小板凝胶治疗重症压疮有较好疗效，可在临床中应用。

Objective：To study the recovery mechanism of allogeneic gel in treatment of severe pressure ul- cer.Methods：13 cases of severe pressure ulcer including 17 wounds, after standard treatment of wounds, the allo- geneio platelet gel was injected into the ulcer surface and sinus. Pressure ulcer scale for healing and pressure ul- cer area and wound healing rate were determined before treatment and after treatment. Results：The score of pres- sure ulcer scale for healing significantly reduced, and the pressure ulcer area significantly reduced. The wound healing rate was 58.82%（10/17）,marked effective rate was 23.52%（4/17）, the effective rate was 17.65% （3/17）, no effect was 0,there was significant statistical significance （P〈0.05）. Conclusion： The platelet gel has good curative effect,it can be used in clinic.