新疆冠心病患者(汉、维)中医体质特点分析及与中医证型的相关性研究

TCM constitutional features and correlation between constitution and syndrome type in patients(Han nationality or Uyghur nationality) with coronary heart disease in Xinjiang

目的探讨新疆汉族、维吾尔族冠心病患者中医体质特点以及体质与证型关联性,为冠心病的临床防治提供依据。方法 2009年10月—2010年10月运用横断面调查的方法,在新疆阿克苏等5个地区10家医院收集生长于新疆或在新疆居住20年以上且经西医确诊第一诊断为冠心病和(或)中医辨病为胸痹的住院患者660例,采用标准化的9种中医体质量表对其实施中医体质辨识和中医证型分类,分析冠心病患者中医体质类型与中医证型之间的关系。结果①汉族、维吾尔族冠心病患者中医体质均以气虚质、痰湿质、血瘀质为主,维吾尔族冠心病患者痰湿质、湿热质与汉族比较差异均有统计学意义(P<0.01);②660例冠心病患者秽浊痰阻证387例占58.63%,非秽浊痰阻证273例占41.37%;③秽浊痰阻证以兼夹、虚实夹杂体质为主,两组体质比较其中阴虚质、痰湿质、湿热质、血瘀质比较差异有统计学意义(P<0.01);④秽浊痰阻证与痰湿质、气虚质、湿热质、血瘀质相关性明显(P均<0.05)。结论饮食习惯是影响体质形成、证候类型的重要因素;秽浊痰阻证以偏颇体质、虚实夹杂体质为主,且与气虚质、痰湿质、湿热质、血瘀质相关。

Objective To discuss TCM constitutional features and correlation between constitution and syndrome type in patients （Han nationality or Uyghur nationality） with coronary heart disease （CHD） in Xinjiang, and provide basis for preventing and treating CHD in clinic. Methods From Oct. 2009 to Oct. 2010 and in 10 hospital in 5 prefectures including Akesu of Xinjiang, 660 hospitalized patients, who grew up or have lived in Xinjiang for more than 20 years and diagnosed firstly as CHD by Western medicine and/or as chest im TCM constitutional types ent by Chinese medicine, were selected by using cross-sectional survey. Their and syndrome types were identified by applying standardized scale of 9 TCM constitutional types. The relationship between TCM constitutional types and syndrome types was analyzed. Results （1）The constitutional types are mainly qi-deficiency constitution, phlegm-damp constitution and blood-stasis constitution in both Han and Uyghur patients with CHD, while there was statistical difference in phlegm-damp constitution and damp-heat constitution between Han and Uyghur patients （P 〈0.01 ）. （2）Among 660 CHD patients, there were 387 with syndrome of dirty-turbid phlegm obstruction （58.63%）, and 273 without this syndrome （41.37%）. （3）The syndrome of dirty-turbid phlegm obstruction was mainly related to combined constitution and mixture constitution of deficiency and excess, and the comparison in yin-deficiency constitution, phlegm-damp constitution, damp-heat constitution and blood-stasis constitution showed statistical significance between two groups （P 〈0.01 ）. （4） The syndrome of dirty-turbid phlegm obstruction was significantly correlated to phlegm-damp constitution, qi-defieieney constitution, damp-heat constitution and blood-stasis constitution （ all P 〈 0. 05 ）. Conclusion Diet custom is an important factor influencing constitutional types and syndrome types. The syndrome of dirty-turbid phlegm obstruction was mainly related to deflective constitution and combined constitution of deficiency and excess, and was correlated to qi-deficiency constitution, phlegm-damp constitution, damp-heat constitution and blood-stasis constitution.