儿童皮肌炎35例临床分析

Clinical analysis of 35 patients with juvenile dermatomyositis

目的研究儿童皮肌炎(Juvenile dermatomyositis,JDM)的临床特点。方法采用回顾性分析方法对1990年4月-2010年3月在本院住院的35例JDM患者进行临床资料分析。结果 35例JDM患者有较多并且较严重的并发症如化脓性感染、肺结核、钙质沉着、肌肉挛缩、心脏受累等,激素等治疗后完全缓解31例,部分缓解2例,未愈1例,死亡2例。结论 JDM是慢性活跃性疾病,结局好坏与治疗是否合适有关,严重的并发症仍然普遍存在。

Objective To analyze the clinical characteristics of juvenile dermatornyositis. Methods Thirty-five patients with juvenile dermatomyositis in Hainan Provincial Hospital were analyzed retrospectively. Results Most of Juvinilee dermatomyositis patients with severe complications, such as pyogenic infections, pulmonary tuberculosis,caleinosis, muscle conutractures and heart involvement,et al. Thirty-one of the 35 patients with juvenile dermatomyositis were totUy relieved,2 partial relieved,one failed and 2 died after treated with coorticosteroids. Conclusion Juvenile dermatomyositis is a chronic inflammatory illness. Functional outcomes are associated with therpied chosen and serious complications are stillcommon.