丁二磺酸腺苷蛋氨酸在肝移植术后早期的疗效观察

Observation on the effect of ademetionine 1,4-butanedisulfonate in the patients after liver transplantation

目的:评估丁二磺酸腺苷蛋氨酸对肝移植术后患者早期的疗效。方法:回顾性分析我院2010年1月–2011年3月106例肝移植术后患者的临床资料,其中,对照组50例,给予常规肝移植术后治疗方案;治疗组56例,除给予常规肝移植术后治疗方案外,同时给予丁二磺酸腺苷蛋氨酸治疗;比较两组患者术后第1、3、7天的肝功能情况。结果:所有肝移植术后患者的肝功能均有所改善,其中,治疗组患者的肝功能改善程度明显优于对照组,差异具有统计学意义(P<0.05)。结论:丁二磺酸腺苷蛋氨酸作为肝移植术后常规治疗药物,具有较高的协同作用。

Objective： To observe and evaluate the forepart effect of ademetionine 1,4-butanedisulfonate in the patients after liver transplantation.Methods： We retrospectively analyzed the clinical data of 106 cases after liver transplantation between January 2010 and March 2011.There were 50 cases as control group with common practice after liver transplantation.The other 56 cases as treatment group got therapy of ademetionine 1,4-butanedisulfonate besides the common practice.The liver function of all the patients in two groups were compared in 1st,3rd,7th day after liver transplantation.Results： The liver function of all patients became better after treatment.The liver function of patients in the treatment group became better than that of the control group,and there was statistical significant difference between the two groups（P 0.05）.Conclusion： Ademetionine 1,4-butanedisulfonate as the common practice in patents after liver transplantation has the cooperative effect.