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老年晚期胃癌两个化疗方案的对比研究 被引量:3

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摘要 目的对比老年晚期胃癌两个化疗方案的疗效和毒副反应。方法 选择42例老年晚期胃癌患者,随机分为A组和B组,A组应用多西他赛、亚叶酸钙和5-氟脲嘧啶化疗(TLF方案),B组应用足叶乙甙、亚叶酸钙和5-氟脲嘧啶化疗(ELF方案),以28d为1个化疗周期,至少完成两个化疗周期后观察患者的近期疗效、不良反应、生活质量和总生存时间、结果,A组的治疗有效率为57.14%,B组为19.04%,两组比较差异有统计学意义(P<0.05)。两组在不良反应、生活质量、中位生存时间和总生存时间方面的差异均无统计学意义(P>0.05)。结论对老年晚期胃癌,TLF方案的近期疗效优于传统的ELF方案,生存时间和毒副反应两者差异无统计学意义。
出处 《中国医药科学》 2012年第4期47-48,共2页 China Medicine And Pharmacy
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