关注抗组胺药治疗慢性荨麻疹应用的策略

Concerned about the application strategy of antihistamines in chronic urticaria

抗组胺药通过拮抗H1受体来阻断组胺与受体的结合,从而影响变态反应发生的过程,是治疗慢性荨麻疹的基本药物。最新研究表明,抗组胺药还可通过其他机制发挥更广泛的药理作用。本文就目前临床抗组胺药物选择及使用的策略进行探讨。

H1 antihistamines, which prevent the proceeding of allergic inflammation through aganist histamine H1 receptor, are more widely used to treat chronic urticaria. In recent studies, H1 antihistamines bring into more extensive pharmacological actions based on some other pathways. Therefore, clinical aplication strategy of H1 antihistamines has been modified. This paper focus on some approachs to these issues.