异维A酸联合除脂生发胶囊治疗脂溢性皮炎疗效观察

Observation on effect of oral isotretinoin and Chu Zhi Sheng Fa capsules for patients with seborrheic dermatitis

目的观察异维A酸联合除脂生发胶囊治疗脂溢性皮炎的疗效。方法将86例脂溢性皮炎患者随机分为两组。治疗组予以口服异维A酸10mg,2次/d;除脂生发胶囊1.98,3次/d。对照组仅口服异维A酸10mg,2次/d。每2周复查1次,记录疗效及副反应,连续观察6周。结果治疗组痊愈率72.0%,总有效率90.6%;对照组痊愈率51.2%,总有效率72.1%。两组间痊愈率及总有效率均有显著差异性(P<0.05)。结论异维A酸联合除脂生发胶囊治疗脂溢性皮炎疗效好,副作用少。

Objective To observe the effect of oral isotretinoin and chu zhi sheng Fa capsules for patients with seborrheic dermatitis.Methods Eighty-six patients with seborrheic dermatitis were divided into two groups at random.The patients of treatment group were given oral isotretinoin and chu zhi sheng Fa capsules.The patients of control group were given oral isotretinoin.The therapeutic effect and the adverse reactions were recorded every two weeks up to a total of six weeks.Results The cure rate and total effective rate in the treatment group were 72.0% and 90.6% respectively,while were 51.2% and 72.1% in the control group.There were significant differences in cure and total effective rates between the two groups（P0.05）.Conclusion Isotretinoin in combination with chu zhi sheng Fa capsules is effective on seborrheic dermatitis with few side effects.