摘要
诱导痰技术是一种无创获取痰液的方法,痰液可以提供呼吸道疾病所引起的细胞和分子改变的信息。越来越多的研究显示,肺癌能够引起痰异质变化,如抑癌基因的过度甲基化,并随着疾病的进展,痰异质变化不断增多。因此,痰细胞学检查联合分子标记在肺癌的早期诊断中有望发挥重要的作用。
Induced sputum is a useful noninvasive method of studying airway diseases and allowing characterization of cells and molecular markers.An increasing number of studies have shown that lung cancer can cause changes in sputum such as hypermethylation of cancer suppressor genes,and these changes positively correlate with disease progression.Therefore,molecular markers plus sputum cytology for early diagnosis is expected to play an important role in lung cancer.
出处
《临床肿瘤学杂志》
CAS
2012年第2期187-189,共3页
Chinese Clinical Oncology
关键词
诱导痰
分子标记
肺癌
早期诊断
Induced sputum
Molecular marker
Lung cancer
Early diagnosis
