银莲花化学成分研究

Chemical constituents from Anemone cathayensis

目的研究银莲花Anemone cathayensis的化学成分。方法采用溶剂法进行提取和萃取,采用硅胶柱色谱、凝胶柱色谱和重结晶等方法进行分离纯化,根据波谱数据进行结构鉴定。结果从银莲花中分离得到11个化合物,分别鉴定为β-谷甾醇(1)、4,7-二甲氧基-5-甲基香豆素(2)、3β-甲氧基-齐敦果-11-酮-18-烯(3)、α-香树脂醇(4)、28-羟基-齐敦果-12-烯-3,11-二酮(5)、熊果酸(6)、28-羟基-α-香树脂醇(7)、青钱柳酸B(8)、2α,23-二羟基-熊果酸(9)、β-胡萝卜苷(10)、槲皮素-7-O-鼠李糖苷(11)。结论化合物1～11均为首次从该植物中分离得到。

Objective To study the chemical constituents of Anemone cathayensis.Methods Some chromatographic methods were used to isolate the chemical constituents from this plant.Their structures were elucidated on the basis of spectral data.Results Eleven compounds were identified as β-sitosterol（1）,4,7-dimethoxy-5-methyl coumarin（2）,3β-methoxyolean-olean-11-dione-18（3）,α-amyrin（4）,28-hydroxy-olean-12-ene-3,11-dione（5）,ursolic acid（6）,28-hydroxy-α-amyrin（7）,cyclocaric acid B（8）,2α,23dihydroxyursolic acid（9）,β-daucosterol（10）,and ereetin-3-7-O-rhanmoside（11）.Conclusion All the eleven compounds are isolated from the title plant for the first time.