注射用红花黄色素联合速效救心丸治疗不稳定型心绞痛疗效观察

The curative effects of safflower yellow pigment injection united Suxiaojiuxin pill to unstable angina pectoris

目的观察红花黄色素注射液联合速效救心丸对冠状动脉粥样硬化性心脏病(冠心病)不稳定型心绞痛患者的临床治疗效果。方法将60例不稳定型心绞痛患者随机分为治疗组30例和对照组30例。对照组患者给予西医常规治疗,治疗组在对照组的基础上加用红花黄色素注射液和速效救心丸,疗程均为2周。观察临床疗效、治疗前后心绞痛发作次数和硝酸甘油的用量,检测2组患者心电图改变情况。结果总有效率治疗组为93%,对照组为73%,2组差异有统计学意义(P<0.05)。2组在治疗后心绞痛发作频率、ST段的移位均明显降低,与治疗前比较,差异有统计学意义(P<0.05);2组治疗后比较,差异有统计学意义(P<0.05)。结论红花黄色素注射液联合速效救心丸能显著改善不稳定型心绞痛患者临床症状,临床治疗效果显著。

Objective To observe the curative effect of safflower yellow pigment injection united Suxiaojiuxin pill to unstable angina Pectoris ,and explore the mechanism and offer the scientific basis for the further clinic application. Methods Totally 60 patients with UAP were divided into two groups randomly： the conventional therapy group （30 cases） and the afflower yellow pigment injection united Suxiaojiuxin pill group （30 cases）. The course of the treatment was 2 weeks. For all the patients curative effect, attack frequency of angina,nitroglycerin consumption, ECG, and signs were all observed. Results The clinical curative effective of angina pectoris symptoms： the treatment group total effective rate was 93%; The control group was 73%. The statistics result shows difference between the treatment group and the control group（P〈0.05 ）. The clinical results showed that angina pectoris symptoms and ECG（ST-segment） after the treatment were lower than before the treatment in the two groups （P〈0.05）. The treatment group was superior to the control group （P〈 0.05 ）. Conclusion This study demonstrated that safflower yellow pigment injection united Suxiaojiuxin pill can relieve symptoms of patients with angina pectoris and improve ECG, syndrome and signs. In a word, the safflower yellow pigment jection united Suxiaojiuxin pill could be used as a sensitive markers. Clinical curative effect is distinct.