大肠杆菌外膜蛋白OmpF结构研究进展

Progresses on Structure of Outer Membrane Protein OmpF from Escherichia Coli

OmpF是大肠杆菌最重要的外膜蛋白之一,它形成的离子通道是大肠杆菌与外界进行物质交换的重要通道,能够使分子量不超过600 Da的水溶性物质通过该离子通道穿越外膜。OmpF外膜蛋白与大肠杆菌的耐药性、抗酸性以及抗渗透压等生理活动密切相关。OmpF的功能与其结构特征密不可分。阐述了大肠杆菌外膜蛋白OmpF及其组成元件Loop 3环的结构特征。

OmpF is the one of the most important outer membrane proteins of Escherichia coli. The ion channel formed by OmpF is the main passage for substance exchange of Escherichia coli with the environment, which allows utes with molecular mass up to ic resistance and anti-osmotic review describes the structure hydrophilic sol600 Da across the outer membrane. OmpF plays crucial roles in the drug resistance, anti-acidpressure of Escherichia coli, which is closely related with the structure of OmpF. The present properties of the outer membrane protein OmpF and its component Loop 3