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miRNAs与心肌肥厚的研究进展 被引量:2

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摘要 心肌肥厚是心血管疾病最为常见的并发症之一,是心肌重构过程中非常重要的组成部分,长期的心肌肥厚很容易导致心力衰竭或猝死[1]。虽然临床上已采取了多种治疗策略,但心衰的发病率和病死率仍不断上升。研究表明,长期压力和(或)容积负荷过度、
作者 黄帅 单志新
出处 《实用医学杂志》 CAS 北大核心 2012年第5期845-847,共3页 The Journal of Practical Medicine
基金 国家自然科学基金资助项目(编号:81070102)
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参考文献15

  • 1Balakumar P,Jagadeesh G.Multifariousmolecular signaling cascades of cardiachypertrophy:can the muddy waters becleared[J]?Pharmacol Res,2010,62(5):365-383.
  • 2Bernardo B C,Weeks K L.Moleculardistinction between physiological andpathological cardiac hypertrophy:experimental findings and therapeuticstrategies[J].Pharmacol Ther,2010,128(1):191-227.
  • 3Cordes K R,Srivastava D.MicroRNAregulation of cardiovascular development[J].Circ Res,2009,104(6):724-732.
  • 4Ikeda S,He A,Kong S,et al.MicroRNA-1negatively regulatesexpression of the hypertrophy-associatedcalmodulin and Mef2a genes[J].MolCell Biol,2009,29(8):2193-2204.
  • 5Li Q,Song X W,Zou J,et al.Attenuation of microRNA-1derepressesthe cytoskeleton regulatory proteintwinfilin-1to provoke cardiachypertrophy[J].J Cell Sci,2010,123(14):2444-2452.
  • 6Duisters R F,Tijsen A J,Schroen B,et al.miR-133and miR-30regulateconnective tissue growth factor:implications for a role of microRNAs inmyocardial matrix remodeling[J].CircRes,2009,104(2):170-178.
  • 7Li Q,Lin X,Yang X,et al.NFATc4is negatively regulated in miR-133a-mediated cardiomyocyte hypertrophicrepression[J].Am J Physiol Heart CircPhysiol,2010,298(5):1340-1347.
  • 8Wang K,Long B,Zhou J,et al.miR-9and NFATc3regulate myocardinin cardiac hypertrophy[J].J Biol Chem,2010,285(16):11903-11912.
  • 9Yang Y,Ago T,Zhai P,et al.Thioredoxin1negatively regulatesangiotensin II-induced cardiachypertrophy through upregulation ofmiR-98/let-7[J].Circ Res,2011,108(3):305-313.
  • 10Nishi H,Ono K,Horie T,et al.MicroRNA-27a regulates beta cardiacmyosin heavy chain gene expression bytargeting thyroid hormone receptorbeta1in neonatal rat ventricularmyocytes[J].Mol Cell Biol,2011,31(4):744-755.

同被引文献21

  • 1王晓虹,刘进军,于玮,苏兴利,高广道.卡托普利影响压力负荷性大鼠肥厚心肌血管紧张素Ⅱ1受体和2型受体表达[J].中国动脉硬化杂志,2006,14(9):750-754. 被引量:2
  • 2Balakumar P,Jagadeesh G.Muhifarious molecular signaling cascades of cardiac hypertrophy can the muddy waters be cleared[J].J Pharma- col Res ,2010,62(5) :365-383.
  • 3Schltiter KD,Wenzel S. Angiotensin II :a hormone involved in and contributing to pro-hypertrophic cardiac networks and target of anti- hypertrophic cross-talks[J]. Pharmacol Ther, 2008 , 119 (3) : 311-325.
  • 4Miyata S,Haneda T.Hypertrophic growth of cultured neonatal rat heart ceils mediated by type 1 angiotensin 1] receptor[J].Am J Phys- iol, 1994,266 : H2443-2451.
  • 5De Mello WC ,Specht P. Chronic blockade of angiotensin I1 AT1- receptors increased cell-to-cell communication, reduced fibrosis and improved impulse propagation in the failing heart[J].J Renin Angiotensin Aldosterone Syst, 2006,7 (4) : 201-205.
  • 6Katsi V, Raftopoulos L, Aggeli C, et al. Tricuspid regurgitation after successful mitral valve surgery [J]. Interact Cardiovasc Thorac Surg, 2012,15( 1 ) : 102-108.
  • 7Di Mauro M, Bezante GP, Di Baldassarre A, et al. Functional tricuspid regurgitation: an underestimated issue [J]. Int J Cardiol, 2013,168(2) : 707-715.
  • 8Hoppe H, Pavcnik D, Chuter TA, et 81. Percutaneous technique for creation of tricuspid regurgitation in an ovine model [J]. J Vasc Interv Radiol, 2007,18( 1 Pt 1 ) : 133-136.
  • 9Buffington CW, Nystrom EU. Neither the accuracy nor the precision of thermal dilution cardiac output measurements is altered by acute tricuspid regurgitation in pigs [J]. Anesth Analg, 2004,98 (4) : 884-890.
  • 10Walter EM, Vasilyev NV, Sill B, et al. Creation of a tricuspid valve regurgitation model from tricuspid annular dilatation using the cardioport video-assisted imaging system [J]. J Heart ValveDis, 2011,20(2):184-188.

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