摘要
目的建立心脑通口服液的质量控制方法。方法采用薄层色谱法对石菖蒲、泽泻、鸡血藤、延胡索进行定性鉴别;以乙腈-水(35∶65)为流动相,以283 nm为检测波长。结果黄芪苷的量在2.68～13.40μg范围内呈良好的线性关系(r=0.9996),回归方程为A=1.6579C+4.7705。精密度试验RSD为1.27%,该方法平均回收率为96.31%,RSD=1.08%。结论该方法对心脑通口服液质量可控。
Objective To develop a method of quality control of xinnaotong oral liquid.Methods Acorus gramineus,alisma orientalis,canlis spatholobi,and corydalis tuber were identified by TLC.The content of Baicalin was detected by HPLC（UV scan at wavelength 283nm,CH3CN∶ H2O（35∶ 65）as mobile phase）.Results Baicalin curvers were linear between 2.68 and 13.40 μg（r= 0.9996）.The mean recovery was 96.31%,and the RSD was 1.08%.Conclusion The method is sensitive and simpler.
出处
《安徽医药》
CAS
2012年第2期175-177,共3页
Anhui Medical and Pharmaceutical Journal
基金
南京军区"122"工程培养项目
南京军区创新基金项目(No08MA054)
安徽省卫生厅临床科研项目(No 2010C097)
关键词
心脑通口服液
质量控制
xinnaotong oral liquid
quality control
