灌服雪莲果粉对小鼠肠道菌群的影响

Effect of Yacon Powder on Intestinal Flora in Mice

目的:研究灌服不同剂量的雪莲果粉后,对小鼠肠道菌群的影响.方法:选用80只昆明种小鼠,随机分成4组,实验组分别灌服0.83g/kg,1.70g/kg和5.01g/kg的雪莲果粉,对照组给予等体积的生理盐水,灌服14d.分别于实验第7天、第14天和停止灌服7d后分析各组小鼠盲肠菌群变化.结果表明:和对照组相比,随着灌服时间的延长,各实验组均可使小鼠肠道中双歧杆菌和乳酸菌数量增加(p<0.05),使大肠杆菌数量减少(p<0.05),说明雪莲果粉具有调节小鼠肠道菌群的作用.

Purpose： The aim of this study was to investigate the effect of oral administration of yacon powder on intestinal flora in mice. Methods： Eighty mice were divided into four groups. The experimental groups were orally administered yacon powder 0.83 g/kg . d,1.70 g/kg . d and 5.01 g/kg . d for 14 d, respectively. The control group received the equal volume of normal saline. The number of microflora in the cecum was determined 7 and 14 days after the commencement of the study and 7 days after the termination of administration. Results. The number of Bifidobacgterium and Lactobacillus significantly increased （p〈0.05） and Enterobacillus decreased （p〈0.05） in experimental groups compared with the control in the intestine and feces, thus demonstrating that yacon powder has a function of regulating the intestinal flora of mice.