2,6-二氯-4-硝基苯胺的合成工艺研究

A STUDY OF SYNTHETIC PROCESS OF 2,6-DICHLORO- 4-NITROANILINE

在盐酸溶液中 ,以对硝基苯胺为原料 ,采用直接氯化法制取了染料中间体2,6-二氯 -4 -硝基苯胺。实验结果表明:在n(对硝基苯胺)∶n(氯气 )=1∶30,通氯时间75min,反应温度0℃ ,并套用母液回收 ,可以获得90%以上的收率。

The dye intermediate 2,6-dichloro-4-nitroaniline was prepared by direct chloridization of nitroaniline in the solution of hydrochloric acid. Experiments proves that when n(p-nitroaniline)∶n(chlorine)=1∶30, chloridiza_tion time=75min, reaction temperature=0℃,and utilizing mother liquid for recovery, more than 90% yield rate can be obtained.