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COX-2与胃肠道间质瘤关系的研究进展

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摘要 环氧化酶-2(COX-2)是前列腺素合成过程中的一种限速酶,参与多种疾病的发病过程,与肿瘤的发生发展和浸润转移密切相关。许多研究表明:COX-2在胃肠道间质瘤中过量表达,主要参与胃肠道间质瘤的血管形成、改变黏附因子活性、促使肿瘤转移、抑制凋亡、抑制肿瘤免疫等。因此,提示COX-2可作为胃肠道间质瘤防治的新靶点。
作者 方萍 何晓彬
出处 《西南军医》 2012年第1期137-140,共4页 Journal of Military Surgeon in Southwest China
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