八味中药水和乙醇提取物对酪氨酸酶的激活作用

Activation analysis for water and ethanolic extracts of eight traditional chinese medicine on tyrusinase

在中药乌发方剂中选用八味中药 ,考察这些中药的水提物和乙醇提物对蘑菇酪氨酸酶激活作用的影响。结果显示 :八味中药的水提物和乙醇提物颜色不同 ;对酪氨酸酶活性的影响与提取物浓度有关 ;其中 ,诃子、夏枯草、黑芝麻、旱莲草、泽兰、潼蒺藜、何首乌的水提物在其相应浓度上对酪氨酸酶激活率分别为 68.97%、1 69.89%、52 .41 %、31 .0 3%、64.1 3%、1 9.31 %、1 7.2 4 % ;而诃子、夏枯草、旱莲草、何首乌、补骨脂的乙醇提物对酪氨酸酶激活率分别为 38.62 %、48.97%、34.48%、86.90 %、62 .0 7%。进一步研究这些具有生理功能的中药对头发色素调空机理具有实际应用价值。

Eight chinese crude drugs were seleted in prescriptions for TCM's black hair. Their water and ethanolic extracts were tested respectively. The activition of them with respect to mushroom tyrosinase were analyzed. Experimental results indicated that : Water and ethanolic extracts's colors had marked difference, and their respective activity to activate mushroom tyrosinase concern concentration. Among them the activation ratio water extracts of Terminalia chebula Retz Prunella Vulgavic L. Seamum indicum L. Eclipta prostrata L . Tribulus terrestris L. Polygonum multiflorum Thunb. Were 68.97%,169.89%,54.41%,31.03%,64.13%,19.31%,17.24%, respectively. The activation ratio of ethanolic extracts for Terminalia chebula Retz Prunella Vulgaris L. Eclipta prostrata L. Polygonum multif lorum Thunb, Psoralea corylifolia L. Were 38.62%, 48.97%, 34.48%, 86.90%, 62.07%, respectively.