山莨菪碱在前切除术后综合征中的应用

Acute Effect of Anisodamine in Patients with Anterior Resection Syndrome

目的:评估山莨菪碱在直肠前切除术后综合征中的治疗作用。方法:从2005年至2010年,对60例直肠前切除术后综合症的患者给予口腹山莨菪碱10mgbid或tid治疗,采集病史并对治疗前后进行Cleveland临床失禁评分并对评分结果进行比较。结果:60例直肠前切除术后综合征的患者中,Dixon手术42例,内括约肌切除术18例。山莨菪碱治疗前后平均Cleveland临床失禁评分别为14分和6分,有显著性差异(P<0.05)。有效率为96.7%(58/60)。结论:山莨菪碱对中低位直肠前切除术后综合征有良好的疗效。

Objective：To assess the Acute Effect of Anisodamine in Patients with Anterior Resection Syndrome.Mehods：From 2005 to 2010,60 patients with Anterior Resection Syndrome were treated for 3 to 14 days with anisodamine 10mg tablets bid or tid.To collect medical history and pre-or post-treatment Cleveland Clinic Incontinence Score.And To contrastive analysis this date.Results：60 patients with Anterior Resection Syndrome,42 and 18 patients were respectively undertaken Dixon and intersphincteric resetion.Pre-and post-treatment Cleveland Clinic Incontinence Score was 14 and 6.There were statistically significant differenc（eP0.05）.Effective rate of Anisodamine for Anterior Resection Syndrome was 96.7%（58/60）.Conclusins：Acute Effect of Anisodamine in Patients with Anterior Resection Syndrome is satisfactory.