摘要
采用薄膜-超声法,对二氢杨梅素脂质体的制备工艺进行了研究,通过单因素和响应面实验确定了最佳工艺参数:卵磷脂和胆固醇比为6.2:1(g:g),卵磷脂和二氢杨梅素比为4.1:1(g:g),超声时间为34min,缓冲液pH为7.0,在此条件下,二氢杨梅素脂质体的包封率为88.58%。此法制备二氢杨梅素脂质体具有操作简便可行,脂质体包封率高、稳定性好等优点。
The membrane-ultrasonic method was used to prepare dihydromyricetin liposome.The optimum conditions were determined by the single factor and response surface tests：the phospholipid：cholesterin was 6.2：1,the phospholipids：dihydromyricetin was 4.1：1,the ultrasonic time was 34min,the buffer solution pH was 7.0.Under the optimum conditions,the encapsulation efficiency was 88.58%.Preparation of dihydromyricetin liposome by membrane-ultrasonic method was simple and feasible,it had high encapsulation efficiency and good stability.
出处
《食品工业科技》
CAS
CSCD
北大核心
2012年第5期254-257,共4页
Science and Technology of Food Industry
基金
江西省重大科技攻关项目(2007BN21000)
关键词
二氢杨梅素
脂质体
响应面法
制备
包封率
dihydromyricetin
liposome
response surface method
preparation
encapsulation efficiency
