WHO儿童基本药物示范目录与WHO基本药物示范目录的对比分析

Comparative Analysis of WHO Model List of Essential Drugs for Children with WHO Model List of Essential Drugs

目的:为我国制定儿童基本药物目录提供参考。方法:2名研究者独立提取并交叉核对新版《世界卫生组织(WHO)儿童基本药物示范目录》(以下简称"WHO儿童目录")和《WHO基本药物示范目录》(以下简称"WHO示范目录")信息,分析两目录的异同。结果与结论:两目录药物中数量最多的类别均是抗感染药,其次是抗肿瘤药、免疫抑制剂和姑息治疗用药物。与WHO示范目录相比,WHO儿童目录明确删除了部分类别,且两目录方框标志的具体药物不一致,采用儿童药物目录有助于提高儿童用药的合理性。

OBJECTIVE： To compare and analyze the latest WHO Model List of Essential Drugs for Children （WHO EMLc） with WHO Model List of Essential Drugs （WHO EML）. METHODS： Detailed information of the lists were extracted independent- ly and cross checked by 2 researchers. Differences as well as similarity between 2 lists were investigated. RESULTS ＆ CONCLU- SION： Number of anti-infective drugs rank first in both lists, followed by antineoplastic, immunopressives and medicines used in palliative care. Compared with WHO EML, several categories are deleted by WHO EMLc and differences exist in drugs marked with the square box symbol. List of essential medicines for children may facilitate the reasonable medication.