摘要
目的探讨腹腔镜肝切除术(1aparoscopichepatectomy,LH)与开腹肝切除术(openhepatectomy,OH)治疗肝癌的临床疗效。方法广州医学院第二附属医院2008年1月至2010年12月期间收治原发性肝细胞癌患者45例,将其分为2组,LH组21例,OH组24例。比较2组患者术中、术后的情况与生存率,评价其疗效。结果本组患者术中失血量和输血量LH组显著高于OH组(分别x^2=3.973,x^2=4.862,均P〈0.05),近期并发症发生率LH组(2例)显著低于OH组(9例)(x^2=4.746,P〈0.05);总住院天数LH组为(17.3±5.0)d,OH组为(21.5±5.1)d,2组比较差异有统计学意义(t=-2.717,P〈0.05)。2组患者随访的总生存率比较差异无统计学意义(x^2=0.172,P〉0.05)。LH组的无瘤生存率为52.4%,显著高于OH组(25.0%,x^2=4.543,P〈0.05)。结论腹腔镜与开腹肝切除均为肝癌治疗的有效方法,腹腔镜术式近期并发症少,住院时间短,但两组总体生存率无差异。
Objective To investigate the efficiency and safety of laparoscopic hepatectomy (LH) and open hepatectomy (OH) in patients with hepatocellular carcinoma (HCC). Methods A total of 45 HCC cases undergoing hepatectomy from January 2008 to December 2010 in our hospital were divided into LH group ( n = 21 ) and OH group ( n = 24). Their clinical efficiency and safety were compared and analyzed. Results The amount of intraoperative blood loss and blood transfusion in LH group were significantly higher than that of OH ( respectively x^2 = 3. 973, x^2 = 4. 862, all P 〈 0.05 ). LH is associated with less postoperative complications and duration of hospital stay, compared with OH (respectively X^2 = 4. 746, t = -2. 717, all P 〈 0. 05 ). Cumulative survival rates in both groups were not statistically significant ( x^2 = 0. 172 ,P 〉 0. 05 ). However tumor-free survival rate in LH was significantly higher, superior to that of OH (x^2 = 4. 543 ,P 〈 0. 05). Conclusions LH and OH are all safe and effective hepatectomy for HCC. LH has the advantage of less complication and shorter hospital stay.
出处
《中华普通外科杂志》
CSCD
北大核心
2012年第2期100-102,共3页
Chinese Journal of General Surgery
关键词
癌
肝细胞
肝切除术
腹腔镜检查
Carcinoma,hepatocellular
Hepatectomy
Laparoscopy