期刊文献+

超声联合微泡开放血-脑屏障及其影像学评价的研究进展 被引量:4

下载PDF
导出
摘要 血-脑屏障(blood-brain barrier,BBB)是存在于血液和脑组织间的一种生物屏障系统,BBB通过限制大分子物质甚至许多小分子物质由血液进入脑组织而对脑组织内环境的稳定起重要作用。病理情况下,由于BBB的存在,许多治疗药物或诊断试剂也难以进入脑组织发挥作用。
出处 《中国医学影像学杂志》 CSCD 北大核心 2012年第2期157-160,共4页 Chinese Journal of Medical Imaging
基金 国家自然科学基金(810006201H1805)
  • 相关文献

参考文献27

  • 1Barnard JW,Fry WJ,Fry FJ,et al.Effects of high intensity ultrasound on the central nervous system of the cat.J Comp Neurol,1955,103(3):459-484.
  • 2Ballantine HT,Bell E,Manlapaz J.Progress and problems in the neurological applications of focused ultrasound.J Neurosurg,1960,17(5):858-876.
  • 3Hynynen K,McDannold N,Vykhodtseva N,et al.Noninvasive MR imaging-guided focal opening of the blood-brain barrier in rabbits.Radiology,2001,220(3):640-646.
  • 4Choi JJ,Feshitan JA,Baseri B,et al.Microbubble-size dependence of focused ultrasound-induced blood-brain barrier opening in mice in vivo.IEEE Trans Biomed Eng,2010,57(1):145-154.
  • 5Yang FY,Liu SH,Ho FM,et al.Effect of ultrasound contrast agent dose on the duration of focused-ultrasound-induced blood-brain barrier disruption.J Acoust Soc Am,2009,126(6):3344-3349.
  • 6Yang FY,Fu WM,Chen WS,et al.Quantitative evaluation of the use of microbubbles with transcranial focused ultrasound on blood-brain-barrier disruption.Ultrason Sonochem,2008,15(4):636-643.
  • 7Chopra R,Vykhodtseva N,Hynynen K.Influence of exposure time and pressure amplitude on blood-brain-barrier opening using transcranial ultrasound exposures.ACS Chem Neurosci,2010,1(5):391-398.
  • 8Hynynen K,McDannold N,Vykhodtseva N,et al.Focal disruption of the blood-brain barrier due to260-kHz ultrasound bursts:a method for molecular imaging and targeted drug delivery.J Neurosurg,2006,105(3):445-454.
  • 9McDannold N,Vykhodtseva N,Hynynen K.Blood-brain barrier disruption induced by focused ultrasound and circulating preformed microbubbles appears to be characterized by the mechanical index.Ultrasound Med Biol,2008,34(5):834-840.
  • 10Bing KF,Howles GP,Qi Y,et al.Blood-brain barrier(BBB)disruption using a diagnostic ultrasound scanner and definity in mice.Ultrasound Med Biol,2009,35(8):1298-1308.

二级参考文献2

  • 1薛洪利,中华医学杂志,1995年,75卷,42页
  • 2陈星荣,全身CT和MRI,1993年,74页

共引文献4

同被引文献82

引证文献4

二级引证文献23

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部