泰州市早产儿视网膜病变筛查结果分析

Analysis of screening results of retinopathy of prematurity in preterm infants in Taizhou

目的了解泰州市早产儿视网膜病变(ROP)的患病情况并分析与ROP相关的高危因素。方法收集泰州市2008年3月至2011年3月286例(572只眼)早产儿和低体重儿ROP筛查资料进行回顾性分析。结果 286例(572只眼)早产儿和低体重儿中,共筛查出36例(72只眼)患有不同程度的ROP,ROP检出率约为12.6%,所有患儿均为双眼患病,其中包括ROP 1期12例(24只眼),ROP 2期14例(28只眼),ROP 3期4例(8只眼),ROP4期2例(4只眼),AP-ROP 1例(2只眼),ROP 5期3例(6只眼),提示早产、低出生体重、缺血和缺氧性脑病、胎盘早剥等影响胎儿发育的相对缺氧因素与ROP的发生密切相关。结论早产、低出生体重及相对缺氧因素是ROP发生的高危因素,早筛查、早发现、早治疗是预防ROP致盲的关键。

Objective To study the prevalence of retinopathy of prematurity（ROP）in preterm infants in Taizhou and to analyse the risk factors for ROP.Methods A retrospective analysis was conducted on 286 premature children from March 2008 to March 2011.Results In all the infants examined,36cases（72 eyes,12.6%）developed ROP,including 12 cases（24 eyes）suffering from stage 1,14 cases（28 eyes）from stage 2,4 cases（8 eyes）from stage 3,2 cases（4 eyes）from stage 4,1case（2 eyes） from aggressive posterior ROP and 3 cases（6 eyes） from stage 5.Clinical analysis indicated that prematurity,low birth weight,hypoxic-ischemic encephalopathy and placenta abruption were closely related to the occurrence of ROP.Conclusion Prematurity,low birth weight and the relative hypoxia are high risk factors for the occurrence of ROP.Early screening,early detection and early treatment are of great importance in preventing from blinding caused by ROP in preterm infants.