二氧化硅负载磷钨钼酸催化合成环己酮1,2-丙二醇缩酮

Catalytic synthesis of cyclohexanone 1,2-propanediol ketal with H_3PW_6Mo_6O_(40)/SiO_2

以二氧化硅负载磷钨钼酸(H_3PW_6Mo_6O_(40)/SiO_2)为催化剂,环己酮和1,2-丙二醇为原料合成环己酮1,2-丙二醇缩酮。探讨了H_3PW_6Mo_6O_(40)/SiO_2对缩酮反应的催化活性,研究了酮醇物质的量比、催化剂用量、反应时间等因素对产物收率的影响。实验结果表明:H_3PW_6Mo_6O_(40)/SiO_2是合成环己酮1,2-丙二醇缩酮的良好催化剂。在固定环己酮用量为0.20mol的情况下,n(环己酮):n(1,2-丙二醇)=1.0:1.3,催化剂用量占反应物料总质量的0.8%,带水剂环己烷的用量为12mL,反应时间45min的条件下,产品收率可达83.95%。

Cyclohexanone 1,2-propanediol ketal was synthesized from cyclohexanone and 1,2-propanediol using H3 PW6 Mo6O40/SiO2 as catalyst. The effect of different reaction parameters, such as mole ratio of cyclo- hexanone to 1,2-propanediol, catalyst dosage and reaction time on the yield of cyclohexanone 1,2-propanediol ketal were discussed and the best reaction conditions were found out. Experimental results showed that H3 PW6 Mo6 O40/SiOz was an excellent catalyst. The optimum conditions are ： molar ratio of cyclohexanone to 1,2- propanediol is 1.0 ： 1.3, the quantity of catalyst is equal to 0. 8 0/00 of feed stocks, the volume of cyclohexane as the water-carrying agent is 12mL, and the reaction time is 45min, its yield can be up to 83. 95%.